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2001 1
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FOXM1 and CENPF are associated with a poor prognosis through promoting proliferation and migration in lung adenocarcinoma.
Li P, Ma G, Cui Z, Zhang S, Su Q, Cai Z. Li P, et al. Oncol Lett. 2023 Oct 17;26(6):518. doi: 10.3892/ol.2023.14105. eCollection 2023 Dec. Oncol Lett. 2023. PMID: 37920441 Free PMC article.
Lung adenocarcinoma (LUAD) is a clinically challenging disease due to its poor prognosis and limited therapeutic methods. ...High expression of FOXM1 and CENPF were associated with poor survival. Furthermore, LUAD cells with FOXM1 and CENPF knockdown showed a …
Lung adenocarcinoma (LUAD) is a clinically challenging disease due to its poor prognosis and limited therapeutic methods. ...High exp …
Overexpression of CENPF is associated with progression and poor prognosis of lung adenocarcinoma.
Li MX, Zhang MY, Dong HH, Li AJ, Teng HF, Liu AL, Xu N, Qu YQ. Li MX, et al. Int J Med Sci. 2021 Jan 1;18(2):494-504. doi: 10.7150/ijms.49041. eCollection 2021. Int J Med Sci. 2021. PMID: 33390818 Free PMC article.
Background and aim: The molecular signatures of lung adenocarcinoma (LUAD) are not well understood. Centromere protein F (CENPF) has been shown to promote oncogenesis in many cancers; however, its role in LUAD has not been illustrated. We explored the role of CEN …
Background and aim: The molecular signatures of lung adenocarcinoma (LUAD) are not well understood. Centromere protein F (CENPF …
CENPF Upregulation is Associated with Immunosuppressive Status and Poor Clinical Outcomes in Lung Adenocarcinoma Validated by qRT-PCR.
Xu Z, Xu D, You Z, Tian W. Xu Z, et al. Comb Chem High Throughput Screen. 2024;27(1):78-89. doi: 10.2174/1386207326666230607125353. Comb Chem High Throughput Screen. 2024. PMID: 37287300
METHODS: CENPF expression profiles were analyzed in the GEO and TCGA databases. qRT-PCR was used to verify CENPF mRNA expression in lung adenocarcinoma cell lines. ...RESULTS: CENPF expression was elevated in 29 types of cancer. CENPF was highly …
METHODS: CENPF expression profiles were analyzed in the GEO and TCGA databases. qRT-PCR was used to verify CENPF mRNA expressi …
Knockdown of CENPF inhibits the progression of lung adenocarcinoma mediated by ERbeta2/5 pathway.
Hexiao T, Yuquan B, Lecai X, Yanhong W, Li S, Weidong H, Ming X, Xuefeng Z, Gaofeng P, Li Z, Minglin Z, Zheng T, Zetian Y, Xiao Z, Yi C, Lanuti M, Jinping Z. Hexiao T, et al. Aging (Albany NY). 2021 Jan 10;13(2):2604-2625. doi: 10.18632/aging.202303. Epub 2021 Jan 10. Aging (Albany NY). 2021. PMID: 33428600 Free PMC article.
Many studies have reported that estrogen (E2) promotes lung cancer by binding to nuclear estrogen receptors (ER), and altering ER related nuclear protein expressions. With the GEO database analysis, Human centromere protein F (CENPF) is highly expressed in lung adenocar …
Many studies have reported that estrogen (E2) promotes lung cancer by binding to nuclear estrogen receptors (ER), and altering ER related nu …
Screening and identification of biomarkers associated with the diagnosis and prognosis of lung adenocarcinoma.
Wang Y, Zhang L, Chen Y, Li M, Ha M, Li S. Wang Y, et al. J Clin Lab Anal. 2020 Oct;34(10):e23450. doi: 10.1002/jcla.23450. Epub 2020 Jul 16. J Clin Lab Anal. 2020. PMID: 32672359 Free PMC article.
In addition, the correlation analysis revealed six genes, including assembly factor for spindle microtubules (ASPM), centromere protein F (CENPF), contactin 3 (CNTN3), catenin delta 2 (CTNND2), PKHD1 like 1 (PKHD1L1), and semaphorin 6D (SEMA6D), and three SNP mutations at …
In addition, the correlation analysis revealed six genes, including assembly factor for spindle microtubules (ASPM), centromere protein F ( …
Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas.
Kim HE, Kim DG, Lee KJ, Son JG, Song MY, Park YM, Kim JJ, Cho SW, Chi SG, Cheong HS, Shin HD, Lee SW, Lee JK. Kim HE, et al. PLoS One. 2012;7(8):e43223. doi: 10.1371/journal.pone.0043223. Epub 2012 Aug 13. PLoS One. 2012. PMID: 22912832 Free PMC article.
Clonogenic and invasion assays of NIH3T3 cells transfected with each of the four amplified genes showed that CENPF, GMNN, and CDK13 were highly oncogenic whereas FAM82B was not. ...Taken together, our results suggest that coincidently amplified CDK13, GMNN, and CENPF …
Clonogenic and invasion assays of NIH3T3 cells transfected with each of the four amplified genes showed that CENPF, GMNN, and CDK13 w …
Transcriptomic data exploration of consensus genes and molecular mechanisms between chronic obstructive pulmonary disease and lung adenocarcinoma.
Zhang S, Pang K, Feng X, Zeng Y. Zhang S, et al. Sci Rep. 2022 Aug 2;12(1):13214. doi: 10.1038/s41598-022-17552-x. Sci Rep. 2022. PMID: 35918384 Free PMC article.
Most current research has focused on chronic obstructive pulmonary disease (COPD) and lung adenocarcinoma (LUAD) alone; however, it is important to understand the complex mechanism of COPD progression to LUAD. ...Fifteen hub genes were identified: GPI, EZH2, EFNA4, CFB, EN …
Most current research has focused on chronic obstructive pulmonary disease (COPD) and lung adenocarcinoma (LUAD) alone; however, it i …
Construction and investigation of a combined hypoxia and stemness index lncRNA-associated ceRNA regulatory network in lung adenocarcinoma.
Guo L, Li H, Li W, Tang J. Guo L, et al. BMC Med Genomics. 2020 Nov 4;13(1):166. doi: 10.1186/s12920-020-00816-8. BMC Med Genomics. 2020. PMID: 33148251 Free PMC article.
Protein-protein interaction network analysis revealed 20 hub genes, among which CENPF, BUB1, BUB1B, KIF23 and TTK had significant influence on prognosis. ...Overall, we identified CENPF, BUB1, BUB1B, KIF23 and TTK as potentially key genes involved in regulating hypo …
Protein-protein interaction network analysis revealed 20 hub genes, among which CENPF, BUB1, BUB1B, KIF23 and TTK had significant inf …
Identification of KIF4A and its effect on the progression of lung adenocarcinoma based on the bioinformatics analysis.
Song Y, Tang W, Li H. Song Y, et al. Biosci Rep. 2021 Jan 29;41(1):BSR20203973. doi: 10.1042/BSR20203973. Biosci Rep. 2021. PMID: 33398330 Free PMC article.
BACKGROUND: Lung adenocarcinoma (LUAD) is the most frequent histological type of lung cancer, and its incidence has displayed an upward trend in recent years. ...We determined the overall and disease-free survival analysis of the seven hub genes using GEPIA. We further fou …
BACKGROUND: Lung adenocarcinoma (LUAD) is the most frequent histological type of lung cancer, and its incidence has displayed an upwa …
CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle.
Huang YG, Li D, Wang L, Su XM, Tang XB. Huang YG, et al. J Transl Med. 2022 Feb 5;20(1):78. doi: 10.1186/s12967-022-03277-y. J Transl Med. 2022. PMID: 35123514 Free PMC article.
RESULTS: The expression of CENPF in human ACC samples, GEO, and TCGA databases depicted that CENPF was overtly hyper-expressed in ACC patients and positively correlated with tumor stage. ...CONCLUSION: The result points out that CENPF is significantly overexp …
RESULTS: The expression of CENPF in human ACC samples, GEO, and TCGA databases depicted that CENPF was overtly hyper-expressed …
62 results